52 Results for "

Boswellia serrata Roxb.

" in MedChemExpress (MCE) Product Catalog:
Products (52)

52 Results for "Boswellia serrata Roxb." in MCE Product Catalog:

9
Engeletin
Engeletin
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9 Publications Verification
Cat. No.: HY-N0436
CAS No.: 572-31-6
Category:  

Plants Flavanonols Liliaceae Flavonoids Microorganisms Phenols Polyphenols Smilacis Glabrae Rhizoma Disease Research Fields Inflammation/Immunology

Target:  

NF-κB

Engeletin is a flavanonol glycoside isolated from Smilax glabra Roxb. , inhibits NF-κB signaling-pathway activation, and possesses anti-inflammatory, analgesic, diuresis, detumescence, and antibiosis effects.
6
(-)-Huperzine A
(-)-Huperzine A
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6 Cited Publications
Cat. No.: HY-17387
CAS No.: 102518-79-6
Synonyms: Huperzine A
Category:  

Alkaloids Neurological Disease Anti-aging Huperziaceae Terpenoids Sesquiterpenes Pyridine Alkaloids Huperzia serrata Plants Disease Research Fields

Target:  

Cholinesterase (ChE) iGluR

(-)-Huperzine A (Huperzine A) is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease .
4
Nitidine chloride
Nitidine chloride
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4 Cited Publications
Cat. No.: HY-N0498
CAS No.: 13063-04-2
Category:  

Alkaloids Rutaceae Zanthoxylum nitidum (Roxb.) DC. Plants Disease Research Fields Isoquinoline Alkaloids Inflammation/Immunology

Target:  

Parasite Apoptosis STAT Topoisomerase ERK FAK p38 MAPK NF-κB

Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis, inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A, ERK and c-Src/FAK associated signaling pathway, also has anti-inflammatory activity. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway .
3
AKBA
AKBA
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3 Cited Publications
Cat. No.: HY-N0892
CAS No.: 67416-61-9
Synonyms: Acetyl-11-keto-β-boswellic acid
Category:  

Triterpenes Terpenoids Boswellia serrata Plants Burseraceae Disease Research Fields Cancer

Target:  

HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Endogenous Metabolite

AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator.
3
β-Anhydroicaritin
β-Anhydroicaritin
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3 Cited Publications
Cat. No.: HY-N1940
CAS No.: 38226-86-7
Synonyms: Cycloicaritin
Category:  

Flavonols Flavonoids Plants Burseraceae Disease Research Fields Inflammation/Immunology Boswellia carterii

Target:  

Interleukin Related TNF Receptor MMP

β-Anhydroicaritin is isolated from Boswellia carterii Birdware, has important biological and pharmacological effects, such as antiosteoporosis, estrogen regulation and antitumor properties . β-Anhydroicaritin ameliorates the degradation of periodontal tissue and inhibits the synthesis and secretion of TNF-α and MMP-3 in diabetic rats . β-Anhydroicaritin decreases the overproduction of NO, IL-10, TNF-α, MCP-1 and IL-6 in inperitonitis mice. β-Anhydroicaritin inhibits the elevation of intracellular Ca 2+, and markedly decreases iNOS protein expression .
2
β-Boswellic acid
β-Boswellic acid
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2 Cited Publications
Cat. No.: HY-N2513
CAS No.: 631-69-6
Category:  

Triterpenes other families Terpenoids Boswellia serrata Plants Burseraceae Disease Research Fields Cancer

Target:  

Lipoxygenase DNA/RNA Synthesis

β-Boswellic acid is isolated from the gum resin of Boswellia serrata with anticancer, antioxidant activity, anti-inflammatory activity and anti-arthritic pain.β-Boswellic acid is an orally active nonreducing-type inhibitor of the 5-lipoxygenase (5-LO) product formation either interacting directly with the 5-LO or blocking its translocation. β-Boswellic acid inhibits the synthesis of DNA, RNA and protein in human leukemia HL-60 cells with IC50 values ranging from 0.6 to 7.1 μM. β-Boswellic acid is promising for research of diabetes, inflammatory and arthritic diseases .
1
(±)-Huperzine A
(±)-Huperzine A
0 Images
1 Cited Publications
Cat. No.: HY-17388
CAS No.: 120786-18-7
Category:  

Huperziaceae Terpenoids Sesquiterpenes Huperzia serrata Plants

Target:  

Drug Isomer Cholinesterase (ChE) iGluR

(±)-Huperzine A is the racemate of (-)-Huperzine A (HY-17387). (-)-Huperzine A is an alkaloid isolated from Huperzia serrata, with neuroprotective activity. (-)-Huperzine A is a potent, highly specific, reversible and blood-brain barrier penetrant inhibitor of acetylcholinesterase (AChE), with an IC50 of 82 nM. (-)-Huperzine A also is non-competitive antagonist of N-methyl-D-aspartate glutamate (NMDA) receptor. (-)-Huperzine A is developed for the research of neurodegenerative diseases, including Alzheimer’s disease .
1
3-Acetyl-beta-boswellic acid
3-Acetyl-beta-boswellic acid
0 Images
1 Cited Publications
Cat. No.: HY-N2075
CAS No.: 5968-70-7
Category:  

Triterpenes other families Terpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

3-Acetyl-beta-boswellic acid is a boswellic acid isolated from Boswellia serrata gum resin .
Phloracetophenone
Phloracetophenone
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Cat. No.: HY-W008226
CAS No.: 480-66-0
Synonyms: 2,4,6-trihydroxyacetophenone; 1-(2,4,6-Trihydroxyphenyl)ethanone
Category:  

Metabolic Disease Plants Curcuma comosa Roxb. Infection other families Ketones, Aldehydes, Acids Phenols Polyphenols Disease Research Fields Zingiberaceae

Target:  

Cytochrome P450 Bacterial Antibiotic

Phloracetophenone (2,4,6-trihydroxyacetophenone) is the aglycone part of acetophenone glycoside obtained from Curcuma comosa Roxb, with cholesterol-lowering activity. Phloracetophenone enhances cholesterol 7α-hydroxylase (CYP7A1) activity . Phloracetophenone stimulats bile secretion mediated through Mrp2 .
11-​Keto-​beta-​boswellic acid
11-​Keto-​beta-​boswellic acid
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Cat. No.: HY-N2056
CAS No.: 17019-92-0
Synonyms: 11-Keto-β-boswellic acid
Category:  

Triterpenes Terpenoids Boswellia serrata Plants Burseraceae Disease Research Fields Cancer

Target:  

Lipoxygenase Leukotriene Receptor NF-κB

11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11-Keto-beta-boswellic acid has the anti-inflammatory activity is primarily due to inhibit 5-lipoxygenase (5-LOX) and subsequent leukotriene and nuclear factor-kappa B (NF-κB) activation and tumor necrosis factor alpha generation production .
β-Elemonic acid
β-Elemonic acid
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Cat. No.: HY-N2454
CAS No.: 28282-25-9
Category:  

Triterpenes other families Terpenoids Plants Burseraceae Disease Research Fields Inflammation/Immunology Cancer Boswellia carterii

Target:  

Apoptosis Reactive Oxygen Species (ROS) COX Endogenous Metabolite Prolyl Endopeptidase (PREP)

β-Elemonic acid is a triterpene isolated from Boswellia carterii. β-Elemonic acid induces cell apoptosis, reactive oxygen species (ROS) and COX-2 expression and inhibits prolyl endopeptidase. β-Elemonic acid exhibits anticancer and anti-inflammatory effects .
Hydrangenol
Hydrangenol
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Cat. No.: HY-N4028
CAS No.: 480-47-7
Category:  

Anti-aging Hydrangeaceae Coumarins Cosmetic Research Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology

Target:  

MMP COX Interleukin Related p38 MAPK ERK Keap1-Nrf2

Hydrangenol is an orally active antiphotoaging compound. It can be isolated from Hydrangea serrata leaves. Hydrangenol prevents wrinkle formation by reducing MMP and inflammatory cytokine expression and increasing moisturizing factors and antioxidant genes level .
Incensole Acetate
Incensole Acetate
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Cat. No.: HY-N4098
CAS No.: 34701-53-6
Category:  

other families Terpenoids Diterpenoids Plants

Target:  

Apoptosis

Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25–35-triggered apoptosis in hOBNSCs .
Velutinam
Velutinam
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Cat. No.: HY-N16516
CAS No.: 146428-62-8
Category:  

Alkaloids Pyrrole Alkaloids Uvaria grandiflora Roxb. Plants Annonaceae

Target:  

Bacterial

Velutinam is an alkaloid. Velutinam can be isolated from twigs of Uvaria grandiflora Roxb. Velutinam shows antioxidant activity. Velutinam can be used in the research of bacterial infections .
AKBA (Standard)
AKBA (Standard)
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Cat. No.: HY-N0892R
CAS No.: 67416-61-9
Synonyms: Acetyl-11-keto-β-boswellic acid (Standard)
Category:  

Triterpenes Terpenoids Boswellia serrata Plants Burseraceae

Target:  

Reference Standards HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Endogenous Metabolite

AKBA (Standard) is the analytical standard of AKBA. This product is intended for research and analytical applications. AKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator.
Jaslanceoside B
Jaslanceoside B
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Cat. No.: HY-N16539
CAS No.: 188300-82-5
Category:  

Gastrodia elata Bl. Orchidaceae Plants Saccharides Monosaccharides

Target:  

Others

Jaslanceoside B is a secoiridoid glucoside found in Jasminum lanceolarium Roxb .
Huperzine B
Huperzine B
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Cat. No.: HY-N2043
CAS No.: 103548-82-9
Category:  

Lycopodiaceae Alkaloids Piperidine Alkaloids Lycopodium serratum Thunb． Pyridine Alkaloids Plants

Target:  

Cholinesterase (ChE)

Huperzine B is a Lycopodium alkaloid isolated from Huperzia serrata and a highly selective acetylcholinesterase (AChE) inhibitor. Huperzine B can be uesd to can be used to improve Alzheimer's disease .
Esculentoside B
Esculentoside B
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Cat. No.: HY-N6032
CAS No.: 60820-94-2
Synonyms: Phytolaccoside B
Category:  

Plants Phytolaccaceae Phytolacca americana L.

Target:  

Cholinesterase (ChE) JNK NF-κB Fungal

Esculentoside B (Phytolaccoside B) is a natural product from the roots of Phytolacca acinosa Roxb. Esculentoside B is neurotoxic to zebrafish larvae, and impairs their central nervous system development. Esculentoside B inhibits inflammatory response and has antifungal activity .
NMac1
NMac1
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Cat. No.: HY-115507
CAS No.: 1332290-68-2
Target:  

AMPK mTOR ERK Oxidative Phosphorylation Reactive Oxygen Species (ROS) Ras

Research Areas:  

Cancer

NMac1 is an orally active Nm23/NDPK activator. NMac1 directly binds to Nm23-H1 and activates the NDPK activity of recombinant Nm23-H1 with an EC50 of 10.7 uM. NMac1 induces AMPK activation and inhibits mTOR and ERK, leading to mitochondrial OXPHOS dysregulation and suppressing mitochondrial ROS production, which in turn induces mitochondrial dysfunction in MDA-MB-231 cells. NMac1 inhibits Complex I activity and suppresses changes in morphology and actin cytoskeleton organization following Rac1 activation in MDA-MB-231 cells. NMac1 inhibits tumor invasion, migration and metastasis. NMac1 is useful for studying metastatic tumors, such as breast cancer. NMac1 can be isolated from the ginger cassumunar Roxb .
Boswellia serrata extract
Boswellia serrata extract
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Cat. No.: HY-N19060
Category:  

Extract

Target:  

Others

Boswellia serrata extract is rich in boswellic acid, which is the main bioactive component responsible for its medicinal effects. Boswellia serrata extract has anti-inflammatory and analgesic properties and can be used in research on osteoarthritis, rheumatoid arthritis, and other inflammatory diseases.
Assay Types